Hotel + Art Museum Chicago

Engage Every Sense

Curiosity shapes every experience at 21c Chicago, where a world-class museum and boutique hotel exist in perfect harmony – all in Chicago’s vibrant River North neighborhood.

collage on wall next to blue butterflies with 2 tipsy chairs

The Current Exhibit

Chief Curator Alice Gray Stites brings Pop Stars! Popular Culture and Contemporary Art to 21c Chicago. This multi-media exhibition illuminates the intersection of celebrity, commerce, technology and the media, and features over 90 works of art by 55 artists from around the world.
View Exhibit

woman getting hand massage

Spa + Wellness

Relaxation, on demand. 21c Chicago has partnered with Soothe to bring you spa-quality wellness on your schedule, allowing you to recharge during your stay. Either in-room or at one of our three on-site treatment rooms, unwind with massage services and unique experience enhancements.

Soothe Spa
woman typing on laptop with white fluffy dog next to her

Pet-Friendly

We take extra good care of your pups at our hotel with in-room bowls and treats.

green penguin with suitcase next to it

The 21c Penguin

Our flock of penguins live across every 21c property, and set the tone for a stay that’s as much about art as it is hospitality. We like to think they inspire a sense of wonder, curiosity, and happiness…feel free to give the big ones a hug.

group of people surrounding bar area with wine and green penguin as bartender

Come Together

Impactful conversations happen when people come together. Our live and virtual event options keep us connected and thinking about what’s now, what’s next, and how we’ll get there, together.

Events Calendar
man working out in fitness center

Stay in Motion

24/7 fitness center with a fully-appointed equipment lineup, including Peloton bikes.