Hotel + Art Museum Chicago

Engage Every Sense

Curiosity shapes every experience at 21c Chicago, where a world-class museum and boutique hotel exist in perfect harmony – all in Chicago’s vibrant River North neighborhood.

collage on wall next to blue butterflies with 2 tipsy chairs

The Current Exhibit

Chief Curator Alice Gray Stites brings OFF-SPRING: New Generations  to 21c Chicago. This thematic group exhibition of 100 multi-media artworks by 60 artists from across the globe highlighting how religious, cultural, familial, and personal rituals shape who we are and how and where we live, love, and learn.
View Exhibit

a woman lying on a bed with a man lying on it

Spa + Wellness

Relaxation, on demand. 21c Chicago has partnered with Soothe to bring you spa-quality wellness on your schedule, allowing you to recharge in-room. Unwind with massage services and unique experience enhancements.

Soothe Spa
woman typing on laptop with white fluffy dog next to her


We take extra good care of your pups at our hotel with in-room bowls and treats.

green penguin with suitcase next to it

The 21c Penguin

Our flock of penguins live across every 21c property, and set the tone for a stay that’s as much about art as it is hospitality. We like to think they inspire a sense of wonder, curiosity, and happiness…feel free to give the big ones a hug.

group of people surrounding bar area with wine and green penguin as bartender

Come Together

Impactful conversations happen when people come together. Our live and virtual event options keep us connected and thinking about what’s now, what’s next, and how we’ll get there, together.

Events Calendar
man working out in fitness center

Stay in Motion

24/7 fitness center with a fully-appointed equipment lineup, including Peloton bikes.